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Elevated MMA levels (greater or equal to 0.4 mcmol/L) may be a more reliable indicator of B12 status, because it indicates metabolic changes more specific to B12 deficiency.4 Norris recommends MMA and serum vitamin B12 tests for vegans, adding, You dont need to get tested just because youre vegan

For researchers and individuals focused on metabolic health rather than just cosmetic changes, this distinction matters enormously

Sun damage or scarring may matter more than age alone

Treatment is typically long-term

Chronic hyperglycemia in diabetes increases the production of AGEs, leading to diabetes related complications

Pain levels at injury sites often decrease measurably