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Daz-Manera, J., Urtizberea, J

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MC4R is predominantly localized within the hypothalamic regions of the central nervous system and is speculated to modulate energy homeostasis and neurobehavioral functions

One possible mechanism involves abnormal cathepsin maturation, which alters its interaction and localization within lysosomes during pancreatitis, enabling cathepsins to hydrolyze LAMP proteins

Studies suggest that reducing these foods can improve weight management, as the body may burn twice as many calories digesting whole foods compared to processed ones

Dietary intake was self-reported via food diaries and is therefore vulnerable to recall bias and under- or over-reporting, particularly among individuals with obesity