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Novo Nordisk said it is not currently conducting any clinical studies to evaluate semaglutide in patients with substance-use disorders or addiction-related illnesses, although changes in alcohol consumption is a secondary goal of a trial it is conducting of semaglutide in combination with other medicines in patients with alcohol-related liver disease
Research published in the Journal of Biological Chemistry found that GHK-Cu "significantly increased gene expression of MMP-1 and MMP-2 at the lowest concentration" tested, but this relationship becomes more complex at higher levels
