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Can Vitamin B12 deficiency anemia lead to complications if left untreated

seen in ~20% of RF+ patients Pulmonary involvement : interstitial lung disease (ILD), pleural effusion, pulmonary nodules, bronchiolitis obliterans Cardiac involvement : pericarditis, myocarditis, accelerated atherosclerosis, conduction abnormalities Ocular involvement : scleritis, episcleritis, keratoconjunctivitis sicca (secondary Sjgrens), uveitis (H20.x code separately) Vasculitis : digital infarcts, skin ulceration, mononeuritis multiplex, mesenteric ischemia (severe/rare) Feltys syndrome triad : RA + splenomegaly + neutropenia associated with M05.0x codes Anemia of chronic disease

2004 Apr 15;150(1):3-18

A Selective, Membrane-Permeable Molecule What makes 5-Amino-1MQ so effective is its intelligent design

[44] [41] Vitamin B 12 is not one of the supplements recommended by the World Health Organization for healthy women who are pregnant, [14] however, vitamin B 12 is often suggested during pregnancy in a multivitamin along with folic acid [45] [46] especially for pregnant mothers who follow a vegetarian or vegan diet

Do not inject if precipitation occurs