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Absolute GH E max values should not be directly compared across species or experimental models because assay methods, baseline correction, anesthesia, sampling design, and physiological GH secretion patterns differ

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In addition, some sHSPs, such as HSPB1/HSP27 and HSPB5, can be phosphorylated through kinase pathways, including the p38/MK2 pathway, which may regulate their chaperone activity, cytoskeletal interactions, and involvement in autophagy-related clearance of damaged cellular components (Ungelenk et al., 2016

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