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The odds ratio for GP diagnosis significantly increased after six months through 24 months after controlling for different risk factors. Based on their findings, the researchers recommend long-term monitoring and further research in patients with Type 2 diabetes who receive GLP analogs

223,224 GLP-1 also inhibits glucagon release from -cells, which is beneficial for reducing blood glucose levels since glucagon promotes hepatic gluconeogenesis

Concomitant medications particularly other glucose-lowering agents such as insulin or sulphonylureas may increase the risk of hypoglycaemia when used alongside retatrutide

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