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But glucagon receptors are also expressed in cardiac tissue, where their activation has two well-documented effects: A positive chronotropic effect increasing heart rate and a positive inotropic effect increasing the force of heart contractions
Slower dose escalation is the most effective single strategy for reducing side effects with both medications
However, not all tested GLP-1RAs have consistently demonstrated reductions in cardiovascular events, and the impact on specific cardiovascular outcomes varied among the effective drugs
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Lying down after eating
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