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A third group have systematic or widespread symptoms characterized by the presence of widespread pain 26 (significant non-urologic pain outside the pelvis), COPC (e.g., fibromyalgia, IBS), 25 widespread psychosocial difficulties (e.g., anxiety, depression, higher levels of current and lifetime stress, early life and adult traumatic events, negative affect, poor illness coping), 36 or poly-symptomatic, poly-syndromic(PSPS) presentation with widespread somatic symptoms across multiple organ systems

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Patients taking warfarin, heparin, DOACs (direct oral anticoagulants), or high-dose aspirin should discuss potential interactions with their provider before starting BPC-157

Since retatrutide is still being investigated, we do not know about its long-term risks