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(A) Distribution of fibrosis, inflammation response, and ischemia-reperfusion score on the pseudo-time trajectory

MDA is a good marker of tissue oxidative stress-related injury in the body (Kaneda and Miyazawa 1987)

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Moreover, MN-mediated administration of liposomal formulations has been shown to diminish drug degradation, enhance bioavailability, and provide regulated or sustained release profiles, establishing it as a highly effective platform for both local and systemic drug delivery [276]