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The gene has been annotated in the human genome on the chromosome X, it is composed of 13 exons encoding only one splice variant, and has been cloned in 1999 (Sloan and Mager, 1999)
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Larazotide (intestinal health) Article: Larazotide: potential for intestinal health Larazotide is a synthetic peptide that shows promise for strengthening intestinal tight junctions to prevent leaky gut syndrome, reducing passage of toxins, bacteria, and undigested food into the bloodstream that triggers inflammation and autoimmune responses
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Abstract Clinical application of anticancer agents has been often hampered by toxicity against normal cells, so the achievement of their cancer-specific action is still one of the major challenges to be addressed