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Obese mouse models (Coskun 2022) show basal energy expenditure +8-12% vs vehicle, a major contributor to the magnitude of weight loss observed in phase II clinical trials
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Its multimodal action on the GBA highlights a promising therapeutic avenue
Tth AE, Walter FR, Bocsik A, Sntha P, Veszelka S, Nagy L, et al
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Shukla D, Mandal PK, Tripathi M, Vishwakarma G, Mishra R, Sandal K
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