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PMID 18843658

Therefore, the present study investigated whether BSO induced ferroptosis in cancer cells, and whether the cellular glutathione level may be a marker for GCLC inhibitor-sensitivity

Disulfide bonds remain stable in the extracellular environment but are cleaved in the reductive intracellular milieu, characterized by elevated glutathione levels, leading to liposomal destabilization and subsequent drug release

[PubMed abstract ( 44

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