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[73] [74] [75] It is synthesized by some bacteria in the gut microbiota in humans and other animals, but it has long been thought that humans cannot absorb this as it is made in the colon, downstream from the small intestine, where the absorption of most nutrients occurs
Maintenance dose 2 to 2.4 mg weekly: use 2.5 mL bacteriostatic water (2 mg/mL) to keep injection volume under 1 mL
People who do not reach total remission can still see a big drop in symptoms
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The 10mg vial is more cost and volume efficient for users running weekly doses above 5mg, providing more than one week of supply at 8mg per week from a single reconstituted vial
FDA labeling for semaglutide specifically notes that delayed gastric emptying may impact absorption of concomitant oral medications
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