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Nephrol Dial Transpl 14:910918

Endotoxins Tested according to USP 85 to confirm absence of harmful bacterial endotoxins

A significant decrease in fat mass [MD 4.78 kg (95% CI, 7.11 to 2.45)

Initial clinical evaluation of tirzepatide included a series of randomised, placebo-controlled Phase I trials designed to assess the safety, tolerability, pharmacodynamics, and pharmacokinetics of the molecule in humans