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The second barrier to an amylin-analog drug was to extend the half-life relative to the first-generation drug, pramlintide, which is injected 3 times daily
Published 2021 Jul 7
CJC-1295 dosing approaches: CJC-1295 without DAC (Mod GRF 1-29): Dose: 100-200mcg per injection Frequency: 2-3x daily with meals or before bed Works synergistically with Ipamorelin/GHRP Short half-life, requires frequent dosing CJC-1295 with DAC: Dose: 1-2mg per week total Frequency: 2-3 injections weekly (or single weekly) Long-acting, elevated GH for days More convenient than without DAC Example: 5mg vial + 2ml water = 2,500mcg/ml 1mg dose (1,000mcg) = draw 0.40ml 100mcg dose (without DAC) = draw 0.04ml Most people use CJC-1295 WITH DAC for convenience
Studies show that B12 deficiency is linked to an increased risk of developing depressive symptoms, mood disorders, and psychosis
In some cases, temporary dose reduction or slower titration may allow your body to adapt while minimizing gastrointestinal side effects
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