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Parker HE, Adriaenssens A, Rogers G, Richards P, Koepsell H, Reimann F, and Gribble FM

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Maintain a log of doses, injection sites, and observations

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5-12 However, in clinical trials, including SURMOUNT-1 for tirzepatide and STEP 1 for semaglutide, participants were permitted to remain on a given dose for up to 4 additional weeks, as needed, to allow for the dissipation of any GI AEs