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Psyllium husk, a popular type of soluble fiber, may improve satiety and reduce post-meal glucose spikes

Yoshimi, A

Ensuring adequate hydration may also be beneficial

Because this is a probiotic approach rather than a pharmaceutical one, the side effect profile is completely different from injectable GLP-1 medications

- Suppress appetite - Slow gastric emptying (food stays in the stomach longer) - Increase feelings of fullness - Reduce calorie intake, often dramatically - Fast initial weight loss - Reduced cravings - Easier adherence to a calorie deficit in the short term From a purely scale-based perspective, GLP-1 medications can appear very effective

The intermediates from de novo lipogenesis in the liver will disrupt mitochondrial function and produce ROS, and then cause endoplasmic reticulum (ER) stress, ultimately leading to inflammation, and the broken cells releasing cytokines will cause more cell death ( The excess free fatty acids (FFAs) and de novo lipogenesis would break the homeostasis of lipid metabolism