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These factors are key regulators of Pparg expression and adipogenic gene networks, which is consistent with the observed transcriptional changes
Further mechanistic studies are also needed to isolate and characterize the bioactive molecules responsible for the observed inhibition, for example, through metabolomics and in vitro assays with purified TMA lyase (CutC/D) to clarify inhibition kinetics
Formulated with Akkermansia muciniphilia, Clostridium butyricum, and Bifidobacterium infantis
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Lincoff has received consulting fees from Novo Nordisk
