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A 2007 study in Chemical Research in Toxicology observed that the free GHK tripeptide quenched 4-hydroxy-trans-2-nonenal a cytotoxic lipid-peroxidation aldehyde via Michael addition at the histidine and lysine side chains, contributing one route to the broader antioxidant profile attributed to the compound (PMID 17672515)
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Each has documented limitations: NSAIDs: Reduce inflammation short-term but inhibit prostaglandin pathways needed for tissue repair
Denatured tirzepatide is less effective or completely inactive
Tetrahexyldecyl ascorbate (THD) , an oil-soluble vitamin C derivative, operates at a neutral pH around 7 - the same comfortable range as GHK-Cu
Three separate vials win on flexibility
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