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Future studies should address the effects of changes in adipose stem cell subtypes and immune cells on the aging of adipose tissue, which may help to develop anti-aging therapies

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What they found: No serious adverse events triggered by AOD-9604 The most frequent side effects: headache (~5 %), occasional fatigue, at the same frequency as placebo No changes in IGF-1 levels, glycemia, blood pressure, heart rate No signals of cardiovascular, hepatic or renal toxicity Safety profile comparable to placebo Why it matters: From a safety perspective, AOD-9604 is one of the safest peptides in the clinical registry

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doi:10.3390/molecules21101351 96

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