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Washington University in St

Significant weight loss is typically observable by this point

At the 4-month mark, participants taking pramlintide experienced weight loss ranging from 3.449 to 6.1 kg, while the placebo group lost only 2.449 kg

D'Ascanio AM, Mullally JA, Frishman WH

Treatment effects estimated using MI With the increasing computational awareness and capacity to develop statistical methods that provide more useful interpretations of the treatment effect, MI methods have become dominant for the reporting of recent weight management clinical trials (e.g., semaglutide obesity phase 2 trial [34] and the SCALE phase 3b trials [7, 8])

EBioMedicine 47:446-456