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The same goes for people with type 2 diabetes who are open to GLP-1 therapy but have hesitated over injections, device handling, or the feel of a more medicalized routine
In LEADER, there was a higher, albeit non-significant, rate of adverse retinal events with liraglutide compared with placebo (HR 1.15, 95% CI 0.871.52
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Root cause analysis
Anything that promotes new blood vessel formation is a theoretical concern in the context of a tumor's blood supply, and the responsible default is caution
Nevertheless, future investigations must establish direct evidence linking specific microbial disruptions to ENS pathology in DGE models or clinical cohorts
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