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Using data from three clinical trials that included 1,119 participants with diabetes, researchers found that people carrying PAM variants generally responded less well to GLP-1 receptor agonists

A major shift is underway in India's obesity and diabetes care, as semaglutide's patent expiry is set to make weight-loss injections far more affordable

The bupropion component carries a boxed warning about increased risk of suicidal thoughts and behaviors, particularly in young adults

Although patients receiving exenatide IR and experiencing longer durations of nausea and vomiting tended to lose more weight, those in the trial group who did not experience the gastrointestinal symptoms (70%) generally lost weight as well (166, 224)

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Shorakae S, Teede H, De Courten B, Lambert G, Boyle J, Moran LJ