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We evaluated the renal cell death by focusing on the RNA expression of apoptosis indicators Bcl-2, Caspase-9, and biomarkers of nephropathy (NGAL, KIM-1)

The Institute of Medicine has not established a tolerable upper intake level of B12 because studies show no adverse health effects when taking excess levels of B12, either through food or supplements

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Ongoing Commitment: Optimal results typically require ongoing treatment, though protocols may be adjusted over time based on progress and goals