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The body-protecting polypeptide (BPC 157 peptide) prepared by the method of the present invention has the advantages of convenient source of raw and auxiliary materials, stable process, high peptide yield, controllable quality, high yield, high purity, low production cost, short cycle, and can be With many advantages such as large-scale production, it fully meets the application requirements of the body protection polypeptide (BPC 157 peptide)