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Vegetarians and vegans tend to have lower dietary intake and typically benefit most from supplementation

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10.1016/0197-2456(95)00134-4 24 JainA

PLoS ONE 3:e1944 Srinivasan R, Ratiney H, Hammond-Rosenbluth KE, Pelletier D, Nelson SJ (2010) MR spectroscopic imaging of glutathione in the white and gray matter at 7 T with an application to multiple sclerosis

Thats a critical distinction, because it means these patches do not actually contain the active GLP-1 medications responsible for the weight-loss effects seen in clinical trials

Because the beta-oxidation of fatty acids requires substantial amounts of oxygen to proceed, this hypoxic environment further stalls the mitochondrial engines