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They reported that Duodopa significantly reduced off periods and increased on time without troublesome dyskinesias

You wouldnt start surgery without sterilizing the instruments, right

They are mild by design, but like any injection, they can cause reactions

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However, if metronidazole causes unpleasant effects such as an upset stomach or stomach pain, taking it with meals or snacks may help

[1] In practice, 1 mL (which provides the full 100 mg of B and B, etc.) is a common dose for general supplementation in deficient states, but clinicians may start with lower volumes for mild deficiencies or in smaller patients