In the Phase 2 trial, fasting glucose increased transiently in some participants, more so at 8 mg and 12 mg, though GLP-1 and GIP co-activation appeared to offset most of this effect
Theres a small wrinkle: the US Food and Drug Administration has yet to officially approve this medication technically called retatrutide but cheekily nicknamed a GLP-3 by users because its still in clinical trials
Individuals who were 21 years of age or older, were at moderate risk for cardiovascular disease, and had a newly filled prescription for SGLT2i, GLP1RA, DPP4i, or SU between January 1, 2014, and December 31, 2021 were considered for the analysis
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Cannula-site reactions, bruising and light-headedness are possible with any intravenous treatment
It adds pancreatitis history, recent surgery and any concurrent weight-loss medications to the same discussion