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Four-point analytical testing Each lot is analysed by HPLC for purity, mass spectrometry for amino acid identity, and LAL testing for endotoxins, with independent third-party verification on top of in-house quality control

Milk thistle is a wild, commonly found plant with wide range of possible health benefits

162 By trafficking cytotoxic agents into exocytic vesicles or blocking nuclear entry, LRP prevents engagement with nuclear DNA or enzymes

In Canada and most of the European Union, its not approved for medical or cosmetic use and is considered an unregulated compound (Health Canada advisory listing AOD9604 as unauthorized)

Sikiric's group in Zagreb has published more than 150 papers on the compound over roughly thirty years, and reporting by Undark in 2026 found that the majority of the existing evidence base comes from that single lab

Their effectiveness largely hinges on being part of a broader, healthier lifestyle, which includes a balanced diet and regular physical activity