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[2] Once administered intramuscularly, B12 is gradually released into the bloodstream and transported to the liver, where approximately half of the body's total B12 stores are held

This guide walks through the entire story in plain English: what peptides are, why pharmacies compounded some of them in the past, what changed in 2023, what Category 2 means, why FDA removed 12 peptides from that category in 2026, what the Pharmacy Compounding Advisory Committee voted to recommend on July 2324, what must happen next, and which five substances FDA expects to review at another meeting before the end of February 2027

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