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In the STEP 1 trial published in The New England Journal of Medicine , people taking semaglutide lost more than 15% of their body weight over about 16 months

Then, depending on whether your B12 deficiency is related to your diet, youll either require B12 tablets between meals or regular injections

This is one of the few peptides where the clinical data actually matches the hype

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There were no episodes of severe hypoglycaemia in either treatment group