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Low GSH levels are associated with a range of chronic concerns and age-related decline
Pawlak, R., Lester, S
Association between metabolic syndrome and the risk of colorectal cancer diagnosed before age 50 years according to tumor location
Supplementary material The Supplementary Material for this article can be found online at: References 1 TalbotKWangH-Y
In addition to counteracting BBB hyperpermeability by inhibiting the production of pro-inflammatory cytokines and ROS, VD has been shown to exert direct effects on ECs by up-regulating the expression of TJ proteins such as zonula occluden (ZO)-1 and claudin-5 while simultaneously down-regulating the levels of cell adhesion molecules such as ICAM-1 and VCAM-1, which collectively promotes the stabilization of the BBB [76]
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