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Zhang W, Mao J-H, Zhu W, Jain AK, Liu K, Brown JB, et al

Physiology of peripheral and central GLP-1 signaling GLP-1 is a 30-amino acid peptide synthetized by enteroendocrine L cells of the small and large intestine, and also in the brain primarily by neurons of the nucleus tractus solitarius (NTS) within the caudal brainstem as a product of tissue-specific posttranslational cleavage of a larger precursor molecule preproglucagon (PPG)

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Its additionally often prescribed off-label to treat insomnia, anxiety, substance abuse disorders, Alzheimers disease, bulimia, and fibromyalgia

Plasticizers, Binders, and Sweeteners Plasticizers such as glycerin may influence strip flexibility, while binders and taste-masking ingredients can affect texture, consistency, and formulation characteristics

The article says this class is most appropriate for adults with a BMI of 27 or above who have a weight-related comorbidity, a BMI of 30 or above without one, or type 2 diabetes