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Cancer Res (2008) 68(23):974653
One removed the first three N-terminal residues, giving the truncated form generally written as DES(1-3) IGF-1
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They did not have Type 2 Diabetes (T2D) but did have Chronic Kidney Disease (CKD) which they defined as estimated glomerular filtration rate (eGFR) 25 and urine albumin-to-creatinine ratio (UACR) 30
[1] Injection site reactions occur when the body responds to the physical trauma of needle insertion, the medication itself, or both
Less common side effects may include fatigue, headaches, dizziness, or injection site reactions
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