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Additionally, some medications can affect glutathione levels

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Protein or zinc deficient diets can alter copper metabolism, so a malnourished individual might observe different outcomes than someone with adequate nutrition

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Regarding conversion, we can cite only a manufacturers claim saying that EAC is metabolized in the skin into pure ascorbic acid (and the ascorbic acid content of EAC is very high - 86,4% - compared to the usual 50-60% Vitamin C content of other derivatives)