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Patients have been "tanked up" with daily injections, followed by weekly and then periodic ones that may continue the rest of their lives
Reduced perceived intoxication could lead to overconsumption or impaired judgment about driving
A person who can absorb dietary B12 can eat meat at any time
Skipping the 7.5mg step and reducing time at each level increases the risk of severe nausea, vomiting, and dehydration
Stress and poor sleep do not directly lower levels, but they increase nutrient demand and can worsen symptoms of existing deficiencies
For example, in mice fed a 4% fat diet, short-term (4 weeks) or long-term (74 weeks) treatment with LA (20 mg/kg body weight) produced no improvement in systemic hypertriglyceridemia (HTG) and hepatic fat contents, and even significantly increased cholesterol content in rat livers despite enhanced mRNA expression of lipid oxidationrelated genes (fibroblast growth factor-21 [Fgf21], peroxisome proliferatorsactivated receptor alpha[ppar], acyl coenzyme A oxidase [acox1], carnitine palmitoyl transferase 1a and 2 [cpt1a and cpt2], recombinant retinoid X receptor a [rxra]), and ATP-binding cassette transporter A1 [abca1])
