Glucagon receptor activation: Increased hepatic glucose output under some conditions, increased energy expenditure, effects on hepatic lipid metabolism
If a patient receives a dosage significantly higher than advised, serious side effects like renal failure or blood poisoning may manifest
GLP-1 Drugs on the Rise The Food and Drug Administration (FDA) has approved a new class of GLP-1 drugs, such as Wegovy, for treating obesity specifically, regardless of a patients history with or without type 2 diabetes
doi: 10.1002/oby.21387 27 TakYJLeeSY
At the same time, selectivity also reduces the risk of certain undesired effects
All such observations derive strictly from in-vitro and animal research and are not statements about human outcomes