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Cultures were then normalized by OD 600 and pelleted by centrifugation (18,000 x g , 10 min, room temperature)

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LncRNA SNHG8 participates in the development of endometrial carcinoma through regulating c-MET expression by miR-152

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27-34 Of note, several trials in the PIONEER program used two estimands to further distinguish their analyses: 1) a treatment-policy estimand, which used data collected at the end of the study period (e.g., week 26 or 52) in the analysis regardless of treatment discontinuation or use of rescue medication

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It is an investigational drug in active Phase 3 clinical trials

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