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Before the cell testing, we analyzed the pH of the samples tested and we excluded the pH of copper compounds as the influencing factor of their potential cytotoxicity (SI 2)
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95% CI, -10.1 to -7.7
The apo system had a more extensive and rugged free energy landscape and number of energy minima (Fig 3AC) than the holo system (Fig 3DF)
Active inflammatory conditions (e.g., untreated rosacea, severe acne) can counteract its remodeling signals
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