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Analysis of the available research reports that tirzepatide administered at 15mg/weekly may result in a hazard ratio (HR) of 0.8 for the incidence of cardiovascular events
Munnich A, Rustin P
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Source: Arrone, et al New England J of Medicine May 11, 2025 Implications for employers: Employers looking to cover GLP-1 medications for weight loss should review formulary options to best balance cost and clinical outcomes
doi:10.1163/156856208784909435
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Good tolerability: Side effects were generally mild and included injection site reactions, headache, and diarrhea
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