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Mechanism of N-dealkylation involves oxidation of - carbon to generate an intermediate carbinolamine which rearranges by cleavage of C-N bond to yield the N-dealkylated product and the corresponding carbonyl of the alkyl group (a primary alkyl is transformed to aldehyde and a secondary alkyl to ketone)
10.1038/nature04089 49 GhaderyC.PirpamerL.HoferE.LangkammerC.PetrovicK.LoitfelderM.et al (2015)
This is the desired dosage that your research protocol or medical advice states
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