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PMID: 34862599 Cells Calcium-Related Genes Predicting Outcomes and Serving as Therapeutic Targets in Endometrial Cancer

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Increased levels of kynurenine catabolites together with tryptophan depletion in the local microenvironment result in metabolic stress on CD4 T cells, leading to impaired T-cell metabolism, impaired antigen-specific response, cell cycle arrest and apoptosis of Th1 cells, inhibition of Th17 cell differentiation, and promotion of Th2 cell polarization [320, 323,324,325]

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Glutathione treatment improved CAP values in ALT responders The median decrease in ALT level from baseline was 12.9%