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If you attempt discontinuation, decide in advance what weight regain threshold will trigger medication resumption
Additional research demonstrated that both liraglutide and sibutramine (a serotonin-norepinephrine reuptake inhibitor) reduced food intake and weight gain in rats provided with chow and a high-fat, high-sugar diet
doi: 10.1016/j.ccell.2021.07.004 249 PetersonEASunJWangJ
Similar phenomena have not been described for plant reductases
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That space is drawing interest from companies trying to recreate parts of GLP-1 biology with biomimetic GLP-1 supplements designed to fit within dietary-supplement rules rather than drug frameworks
