Inhibiting key metabolic nodes such as FAO, HBP, or -KG signaling in TAMs can restore antigen presentation and enhance T-cell-mediated cytotoxicity
The choline metabolite, betaine, can also provide a methyl group for the conversion of homocysteine to methionine
Health 12 , e685e696 (2024)
The specific monitoring protocol should be individualized based on patient risk factors, treatment indication, and duration of therapy
The UK's Leading Dihexa Resource Evidence-based information on Dihexa (PNB-0408)
Investigation also should be undertaken to assess the synergies of these combinations against adult forms, other schistosome species, and schistosome infections in laboratory rodents