[2] [6] In healthy adults, vitamin B 12 deficiency is not common, mainly because body stores of the vitamin are substantial and turnover is slow, with relatively low dietary requirements
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These data demonstrate that high OxPhos signalling is associated with 5FU resistance and suggest that enhanced mitochondrial metabolism promotes treatment failure clinically
Consequently, both developing and developed countries call for an acquisition of the necessary riboflavin levels by readily available and cost-efficient supplementary means 22
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