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Summary: The correct dosage of B12 for healthy UK adults is 1.5 micrograms daily for maintenance, whilst treatment of deficiency requires substantially higher doses of 1,0002,000 g orally or 1 mg intramuscular injections

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That shared architecture is what makes a single peptide capable of engaging all of them

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For instance, a small proportion of people have genetically low b12 values, while they do not have a deficiency