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Wharton, S., Blevins, T., Connery, L., Rosenstock, J., Raha, S., Liu, R., Ma, X., Mather, K
Leptin suppresses the orexigenic effects of NPY while promoting the anorexigenic pathway via POMC/CART activation, decreasing food intake and promoting weight loss
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This review synthesizes evidence from about 120 preclinical/clinical studies sourced from PubMed, Scopus, and Web of Science using keywords (e.g., nutraceutical-drug interactions, bioavailability, CYP/P-gp modulation), prioritizing recent advances (20152024) alongside seminal works to contextualize mechanisms
Plant glutathione S -transferase classification, structure and evolution
