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September 2023: FDA added ileus to Ozempic's warning label
France NL, Syed YY
Nevertheless, as discussed above, a clinically relevant effect of once-daily oral semaglutide was observed with respect to improvement of glycaemic control as well as body weight reduction, both in the current multiple-dose trial and in the phase II trial [10]
Occasional mild injection-site reactions (redness, itch) may occur with subcutaneous administration
How Do the Side Effects of Semaglutide Compare with Those of Other Drugs
Phase 3 clinical trials testing GLP-1 RAs for weight management have demonstrated mean weight reduction of 8% to 15%, with 63% to 86% of patients achieving a 5% or greater reduction in body weight, and 33% to 69% achieving a 10% or greater reduction after 13 to 17 months of use
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