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Mahaffey et al

doi:10.1159/000342534

The reason why the drugs should be included in the EML is because there is existing evidence that points to their possible utility in the management of type 2 diabetes particularly when they are undertaken in patients who also have comorbidities such as cardiovascular disease, chronic kidney disease and in cases that are underscored by obesity

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Additionally, a study that administered vitamin B-12 to rats with a high-fat diet showed that the rats did not gain as much weight as their counterparts who didnt receive the vitamin

Molecular biological significance of lactylation Lactylation plays a pivotal role in orchestrating diverse molecular biological processes, involving DNA, RNA, and proteins