To explore whether TECs ferroptosis exacerbates renal fibrosis through these profibrotic factors, we examined their expression in obstructed kidneys treated with Fer-1
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Martines AM, Masereeuw R, Tjalsma H, Hoenderop JG, Wetzels JF, Swinkels DW (2013) Iron metabolism in the pathogenesis of iron-induced kidney injury
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Researchers have noted that these observations might imply a role for T4 in promoting angiogenesis through regulation of these critical pathways
While still in the research phase and untested in humans, FOXO4-DRI represents a groundbreaking approach to addressing pulmonary fibrosis